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Lecture 20

L & S C30Y Lecture 20: Lecture 20
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7 Pages
30 Views
Spring 2017

Department
Letters And Science
Course Code
L & S C30Y
Professor
Urnov Fyodor
Lecture
20

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Lecture 20 4/6/2017 2:11:00 PM
SprinterUsain Bolt
Fast twitch muscle fibers make the difference
Also being Jamaican probably helpslow Hemoglobin and Early
Training
People have gene variants that do the same thing as blood doping.
The Start of the alpha Actinin 3 Story
Important molecule for muscle development
If someone with a disease is missing it, how do we know if that
mutation is causing the disease?
Alpha Actinin 3 genotype is associated with elite athletic
performance
The X allele causes loss of alpha actinin 3
The pitchas in sales pitch
Know and understand the type of sports your body is optimal for on
a genetic level
But… Genotype is not destiny
Spanish elite long jumper, two times Olympian, (Faster and longer)
with no alpha-actinin-3 in skeletal muscles?
FDA shut down gene screening. Cal got in trouble for doing it for free for
incoming freshmen.
Anatomy of Human Vision
Light goes in through the front, but gets interpreted in the back
3 cone types for three primary color perception
o red
o green
o blue
Visual Acuity Varies in the Population
What does 2020 mean?
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find more resources at oneclass.com
o At 20 feet from that eyechart, you are able to distinguish
what people can read at 20 feet
2030
o at 20 feet, you can distinguish what people can read at 30
feet
An Action Potential—the “thought” of a single neuron
A reflex loopno brain involvement150 msec
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find more resources at oneclass.com

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Description
Lecture 20 4/6/2017 2:11:00 PM Sprinter—Usain Bolt • Fast twitch muscle fibers make the difference • Also being Jamaican probably helps—low Hemoglobin and Early Training People have gene variants that do the same thing as blood doping. The Start of the alpha Actinin 3 Story • Important molecule for muscle development • If someone with a disease is missing it, how do we know if that mutation is causing the disease? • Alpha Actinin 3 genotype is associated with elite athletic performance • The X allele causes loss of alpha actinin 3 The pitch—as in sales pitch • Know and understand the type of sports your body is optimal for on a genetic level But… Genotype is not destiny • Spanish elite long jumper, two times Olympian, (Faster and longer) with no alpha-actinin-3 in skeletal muscles? FDA shut down gene screening. Cal got in trouble for doing it for free for incoming freshmen. Anatomy of Human Vision • Light goes in through the front, but gets interpreted in the back • 3 cone types for three primary color perception o red o green o blue Visual Acuity Varies in the Population • What does 2020 mean? o At 20 feet from that eyechart, you are able to distinguish what people can read at 20 feet • 2030 o at 20 feet, you can distinguish what people can read at 30 feet An Action Potential—the “thought” of a single neuron A reflex loop—no brain involvement—150 msec Baseball players tend to have really good vision, better than 2020 Should genetic testing of student athletes be allowed? Made mandatory? Can we breed for athletic performance? • In horses, we can. o Secretariat: 1973 Triple Crown o Seattle Slew 77 Triple Crown ▪ Wanted to run o American Pharoah: 2015 riple Crown ▪ Product of highly selective breeding ▪ One of the descendants of Secretariat ▪ Northern Dancer is TWO of the 32 great-great- grandparents • Also in greyhounds • Can we do this in humans? o Mitch Larkin and Emily Seebolm—Australia; swimming o Ashton Eaton (US) and Brianne Theisen-Easton (Canada)— track and field o Their kids would be influen
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