Lecture 24: Brain
Bryan Charnley and Flupenthixol
Suffered from schizophrenia
Tapered a medication and painted self-portraits
Flupenthixol was a dopamine receptor antagonist
Dopamine is a psychotropic neurotransmitter (ie. allows neurons to communicate)
Controlling the action in the brain of a single chemical has such a giant effect on personality!
Addictive drugs work by mimicking natural neurotransmitters!
Synapse: where two neurons meet
Neuron release neurotransmitter (ex. dopamine). Receiving neuron has a protein that recepts
Qualia: “the way things seem to us” (the subjective experience of the redness of red)
There is no Cartesian theatre! (ie. someone in your head)
→ but we don’t know how/where self-awareness comes from
Artificial intelligence people and neuroscientists look at the head and tail, but not the whole
Hard to study sentience because it’s not the same in monkeys or crows!
The Visual System and LSD
The world we perceive is not the world that is. It’s what we see in the brain.
1) Acquire the signal
- Light comes into the eye
- Signal is transmitted to optical nerve
2) Transmit the signal 3) Process the signal
- visual cortex
4) Interpret what the signal means (like facial recognition)
- done outside of the visual cortex
Eyes-closed LSD MRI scans shows that the visual cortex activates.
LSD is an agonist: a chemical that turns on a protein
(Antagonist: turns off a protein)
Permuting/affecting neurotransmission in the primary visual cortex
Conclusion: you look with your eyes, but