NUSCTX 103 Lecture Notes - Lecture 1: Proton-Pump Inhibitor, Enterochromaffin-Like Cell, Stomach

• School: Berkeley
• Department: Nutritional Sciences And Toxicology
• Course: NUSCTX 103
• Professor: Olzmann

Document Summary

Study guide for lecture 1: digestive physiology: describe how parietal cells mediate acidification of the stomach. Ecl cells (enterochromaffin-like cell/ m & g) Receptors: m- muscarinic (ach), h2- histamine, g- gastrin. Duodenum/jejunum (upper 40%) : carbs, lipids, amino acids (macronutrients), calcium & : bile & pancreatic juices enter in d, protein dig. in dj, lipid in d, carb in iron. (leftover/undigested to li for fermentation or cellulose/fiber: describe how the surface area of the intestinal mucosa can be 200 m^2. V illi on mucosal surface with m icrovilli (on brush border - microvilli-covered surface of epithelium ) In brain, stomach, & si: cephalic > stimulation ( sensory input of food > vagus nerves stimulate gastrin secretion from g cell > ecl (histamine) & parietal cell secretions (hcl), gastric > secretion ( distension of stomach > parasympathetic medulla. 3) oblongata stimulates stomach secretions (hcl~) & local inc. stomach secretions)