ANTH 242 Lecture Notes - Lecture 2: Diurnal Cycle, Adrenocorticotropic Hormone, Rheumatoid Arthritis

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What are catecholamines: catecholamine is a name given to a class of hormones with a specific structure. Only about 2% comes from the chromaffin cells. Where does norepinephrine leak from: lungs (30%, kidneys (25%, skeletal muscles (22%, liver and related circulation (6%) Skin (5%: heart (3%, adrenal glands (25%) Catecholamine have their effects on tissues by stimulating cell membrane receptors (alpha and beta). Epinephrine excites both types, norepinephrine excites mostly alpha receptors. What is cortisol: a glucocorticoid hormone; key regulator of glucose metabolism. It is secreted by the adrenal gland, specifically in the adrenal cortex. Cortisol has a normal permissive function meaning that it is involved in normal tissue regulation if you had no cortisol nothing would work. Cortisol has regulatory control over stress related processes. Primary regulatory of cortisol is adrenocorticotropic hormone (acth) which is produced in the pituitary gland: acth is regulated by the hypothalamus through the release of corticotrophin releasing factor (crf)

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