BIOL 401 Lecture Notes - Lecture 10: Start Codon, Polyadenylation, Leucine
28 Feb 2017
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When they become less positively charged dna loosens and can trigger the expression of different traits. Turning on a certain gene via methylation of histones/dna can make a certain disease be expressed. Two individuals with the same gene may not both display the same phenotypes due to methylation. Extract dna and treat with sulfide, which will. Actual amino acids won"t change, only whether or not it"s activated convert c as long as c"s aren"t methylated. These act directly upon transcription and control gene expression. Gc box: high concentration of g/c, usually 100-300 base pairs upstream recognized by proteins ~ bind to promoter elements. Caat box: high concentration of caat, about 80 base pairs up". Transcription regulatory regions (above): sequences that if changed they will affect whether transcription is high or low. Promoter bashing: experiment that showed changing the different boxes (tata, Gc, caat) will affect the overall transcription (right) Will be on the same chromosome as the gene of interest.
