Functions of blood: transportation, protection, regulation, ph, temperature. All formed elements originate in the red bone marrow. Disorders of red blood cells: anemia, the blood"s ability to carry oxygen is reduced, can result from too little hemoglobin, too few red blood cells, or both, symptoms include fatigue, headaches, dizziness, paleness, breathlessness, and heart palpitations. Iron-deficiency anemia: most common form, leads to inadequate hemoglobin production, causes, a diet that contains too little iron, an inability to absorb iron, blood loss, hemolytic anemia, occurs when red blood cell destruction exceeds production, causes: Rh factor: another important blood antigen, an rh-negative person will not form anti-rh antibodies unless he or she has been. Individuals who have rh antigens on their rbcs are rh-positive. Individuals who lack rh antigens on their rbcs are rh-negative exposed to the rh antigen: how do you get exposed to the rh antigen, transfusion, having given birth to an rh-positive baby.