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Lecture 4

CAS BI 106 Lecture 4: Anatomy Lecture 4

4 Pages

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CAS BI 106
Dale Pasino

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Lecture 4 13017 THE SKIN Integument Means a covering, refers to the organ system made up of the skin, hair and nails Cutaneous relating to the skin Dermisa specific layer of the skin (lower) Dermatologythe branch of medicine concerned with the skin Functions of the skin Protection from the outside world (disease etc) Control of water loss Temperature regulation Metabolic regulation Immune defense Nutrient storagesynthesis (vitamin D) Sensory reception (how to react to the outside world) excretion Structure 3 main layers o Dermis core center (mostly connective tissue) (pinkish color) o Epidermis on dermis (stratified squamous epithelium, keratinized dead skin) o Hypodermis under dermis (has adipose tissue) (beige color) Deep fascia junction between the skin and the muscle underneath (pearly white) Epidermis Avascular (lack of blood vessels), nutrients diffuse from dermis to supply nutrients Stratified keratinized squamous epithelium Strata of the epithelium have names o Stratum corneum (dead cells) (white specks) (look like stacked cornflakes on top of each other, brittle appearance) We can lose corneum with no impact on our skin o Stratum lucidum (clear cells) (thick) (1or 2 cells thick, lucid means clear) Cant really see it o Stratum granulosum (granule containing cells) filled with dark colored granules (pigment containing vesicle, pigment is called melinine, its your skin color) o Stratum spinosum (spindle shaped cells) (football shaped) o Stratum basale (base or bottom) (rebuilds the new cells) (rounder, more cuboidal shape) Single layer of cuboidal to low columnar stem cells o All cells in the epidermis are called keratinocytes The life of a keratinocyte Dead cells are constantly sloughed off the stratum corneum The stratum corneum remains a consistent size because new cells are always being added from the basal side (stratum lucidum or granulosum)
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