CAS BI 315 Lecture Notes - Lecture 22: Afferent Arterioles, Efferent Arteriole, Proximal Tubule

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The mechanism is not really known the slits are actually larger than proteins, but proteins still don"t move through. Capillaries allow more plasma out per unit time. Starling"s forces determine this: renal disease: protein starts to leak back into the proximal tubule and you lose a lot of protein in the plasma, resulting in more fluid in the plasma and interstitium. Rate at which fluid leaves the capillary and enters all the nephrons per minute. Shuts down for a little while to decrease the amount of fluid coming into the capillaries and decreasing the glomerular pressure, so the gfr goes down. Sympathetic nerve endings cause this *norepinephrine acts on muscle cells in the afferent arteriole causes them to contract, constricting the arteriole and decreasing the. Gfr: once filtration occurs, the first thing that happens is it enters the tubule o 1) glomerular filtration: filtration happens whether it"s a good or bad substance.

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