Class Notes (837,548)
United States (325,103)
Biology (713)
CAS BI 315 (110)
Lecture 6

Lecture 6 BI315.docx

4 Pages
173 Views
Unlock Document

Department
Biology
Course
CAS BI 315
Professor
Eric Widmaier
Semester
Spring

Description
Lecture 6 02/16/2014 Glial cells­kind of cells in the nervous system Subtypes; different glia do different things ▯they have a structural role, metabolic role, blood/brain barrier. Blood/brain barrier­toxins are excluded from leaking out into the brain­glia cells act as a filter around  capillaries: protective mechanism that shields the brain.  Myelin wrapping around (forming layers of their membrane) around the axon.  Glia cells in CNS­form myelin sheaths=oligodendrocytes  Physically support the axon Development of where the axon goes Prevents leakage across the membrane PNS­Schwann cells(glia cells) What would happen if it didn’t work? If the myelin wasn’t sufficient? ▯congenital hypothyroidism­too little  thyroid function. Occurs because of iodine deficiency in pregnant women. Iodine is necessary for thyroid  hormones; iodine is the vertebrate developmental hormone. Iodine deficiency: nervous system forming  without normal synapse connection=mental retardation (cretinism) not reversible unless recognized 6  weeks after birth.  Normal myelination, but lost during adulthood? Demyelination­loss of myelin­autoimmune disease, the  immune system recognizes something about myelin and attack it. Multiple Sclerosis (chronic) and Guillain­ Barre (acute inflammatory demyelinating polyneuropathy) ­ peripheral NS Schwann cell disease (can  overcome this). Both diseases are independent of each other. These diseases can be acquired by: being  exposed to a foreign virus/bacteria and the immune system attacks it but some part of the foreign organism  is similar to myelin and the immune system recognizes that and attacks myelin as well. Wax/wane presence  of the disease. If you have one autoimmune disease, is it more likely you can acquire another? Yes.  Synapse Figure 6.27, Ca2+ triggers exocytosis; active zone, where vesicles are waiting at the docking site.  Voltage gated Ca2+ channels at th
More Less

Related notes for CAS BI 315

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit