CAS BI 315 Lecture Notes - Lecture 20: Extracellular Fluid, Red Blood Cell, Hemoglobin
15 Jan 2017
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At rest, the net flux between the two sides is 0 when there is equal oxygen on each side. Favor movement of oxygen into the side with less free oxygen. Hemoglobin in plasma acts as a way to increase how much oxygen is in the plasma compartment. Increase the total capacity for oxygen by adding hemoglobin. Its not linear. o at any given time, hemoglobin can have 4, 3, 2, or 1 oxygen bound to it o figure 13. 26 100 mmhg po2 is the lung/loading region of the curve (hb+o2=hbo2). This reaction is the reverse of the lung/loading region. If the pressure is high oxygen associates, if the pressure is low oxygen disassociates. Law of mass action in the lungs, o2 is very high which drives the reaction from left to right. 13. 28: movement of oxygen: oxygen molecule comes into the alveolus, through the type 1 cell of the capillary wall, and dissolves in the plasma of the capillary.
