CAS PS 101 Lecture Notes - Lecture 5: Cytoarchitecture, Neuropsychology, Lesion
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Problems with neurons: autism: neuron development. One axon and multiple branches at terminal. Leads to overstimulation: propagation in multiple directions, neural transmission. Phrenology: franz joseph gall (1820s: study of external shape of skull = fail. Lesion studies: pierre flourens (1825: surgical ablation destroyed different areas of brain. Neuroanatomy: santiago ram n y cajal (1852-1934: identified and documented different neuron types, neurons are polar , theorized progression of signal action potentials = dendrite to axon. Cytoarchitecture: koribian broadman (1868-1918: mapped out different areas, cellular structure of brain, numerical system of mapping the brain. Neuropsychology: paul broca (1861) and carl wernicke (1879: stroke => damages to brain; dysfunction of regions; damage inconsistent. Different behavioral deficits for same general area. Neurophysiology: david hubel and torsten wiesel (1959 in boston: electrodes into single neuron of brain in cats, listen to discharge of aps. Functional neural images: suji ogawa (1990)- recorded first image of brain as it processed information;