CAS PS 211 Lecture Notes - Lecture 29: Phagocyte, Leukopenia, Bone Marrow
Document Summary
Normal microbiota and nonspecific resistance: relationships assist in preventing overgrowth of pathogens, microbial antagonism. Opportunistic- may cause disease if environment conditions change- e coli, s aureus, s epermidis, enterococcus faecalis, p aeruginosa, oral streptococci. Phagocytosis: ingestion of microorganism or other particles such as debris by a cell, method of nutrition of some protozoa. Blood consists of fluid called plasma which contains formed elements (cell & cell fragments) During infection, total #of wbc increases as protective response to combat microbes leukocytosis , leucopenia- decreae in leukocyte count (impaired wbc production or effect of increased sensitivity of wbc to damage by complement) Differenital wbc count calculation of % of each kind of white cell in sample of 100. Agranulocytes- have granules but not visible under microscope, monocytes- not actively phagocytic until leave circulating blood, enter body tissues, and mature into macrophages (dispose of worn out cells)