CAS PS 332 Lecture Notes - Lecture 6: Innate Immune System, Phagosome, Adaptive Immune System
22 May 2019
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Document Summary
Meeting space for different types of immune cells: physical barriers, e. g. skin & mucous membranes (digestive, respiratory, & reproductive tracts) Innate immune system ( nonspecific : available from birth, fast, non-specific response, acquired immune system ( specific , develops ~1 week after birth, developed to fight viruses (relatively new threat, slower, specific response. Innate immune system: nonspecific immunity, second line of defense, macrophage: defender cell that is programmed to recognize common antigens, attracted to chemicals released by antigens, travels to site of antigen, reaches out and grabs antigen- phagocytosis, phagocytosis. Seen by t-cells (acquired immunity: cytokines and inflammation are impacted by stress. Ie. flu protects from flu, not measles: so . Antibodies produced: secondary = subsequent encounters, full response within a few days (rather than 1-2 weeks) Innate vs acquired immunity: specificity, any antigen vs. cognate antigen, timing. Interactions between immune system and other parts of the body. Immune-brain links: brain and immune system form bidirectional communication network.
