CGS NS 202 Lecture Notes - Lecture 11: South Platte River, Endocrine Disruptor, Alkylphenol
Document Summary
Lecture 11: other pollutants with endocrine disrupting effects. Pollutants: any agent that adversely affects the health, survival, or activities of living organisms or that alters the environment in undesirable ways. Types of pollutants: water soluble pollutants, move rapidly and widely through an environment, fat soluble pollutants. Inside organisms, they absorb into tissues and cells: stored in lipid (fat) deposits, protected from metabolic breakdown, passed by breast milk to young in mammals, tend to have much longer effects, can bioaccumulate generation to generation. Impaired testicular development wastewater treatment plants on the south platte river and boulder creek. There are many reports of alkylphenols causing production of a female associated liver protein, vitellogenin, in male fish ~epa. Bioaccumulation: process by which cells absorb and store a great variety of molecules, allows cell to accumulate nutrients and essential minerals (like calcium, phosphorus, etc. ) In rats causes liver cancer, pituitary tumors, leukemia, lymphoma, and intestinal cancer.