CGS NS 202 Lecture Notes - Lecture 1: Friedrich Miescher, Linus Pauling, Martha Chase
17 Oct 2017
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Ns lecture 1/27: history of dna, 1868- friedrich miescher found dna in the nucleus of the white blood cells, 1948: linus pauling studied chemical bond theory. Learned about how hemoglobin and collagen are structures. **discovered that proteins are arranged in a double helix*: 1950: martha chase and alfred hershey reveal that viruses replicate by replicating dna, not protein, they knew about dna being organized into chromosomes and that. Dna contains sugar phosphate molecules and nucleic acids. Germ cells do not have 2 copies because they can fertilize with another cell: females have xx and males have xy. Data for dna structure: x-ray crystallography, the source of data for dna was ^ Deoxyribonucleic acid (dna: double helix with two strands, sides of the strands are made up of a sugar and phosphate, connected by bases (adenine-guanine) (thymine-cytosine, anti-parallelism of dna strands: chemical structures are numbered. Even though the two strands are chemically identical, they are arranged in a different way.
