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Class Notes for Neuroscience at Boston University

Neuroscience
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CAS NE 525 Lecture 15: NE525 Biology of Neurodegenerative Diseases, Lecture 15
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ALZHEIMERS DISEASE Two molecular pathways associated with lesions ...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 12: NE525 Biology of Neurodegenerative Diseases, Lecture 12
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PRIONS DISEASE (CJD/MAD COW) Transmissible Spongiform Encephalopat...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 13: NE525 Biology of Neurodegenerative Diseases, Lecture 13
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MULTIPLE SCLEROSIS Neurodegenerative Autoimmune Disease that progr...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 11: NE525 Biology of Neurodegenerative Diseases, Lecture 11
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How are SOD1 aggregates toxic Mitochondrial dysfunctions and apopt...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 14: NE525 Biology of Neurodegenerative Diseases, Lecture 14
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Pathology of MS over time Lesions scarring tissue caused by rele...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 16: NE525 Biology of Neurodegenerative Diseases, Lecture 16
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Trafficking of APP Biosynthetic pathway: proteins, whether they a...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 2: NE525 Biology of Neurodegenerative Diseases, Lecture 2
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PROTEINS MISFOLDING, AGGREGATION AND NEURODEGENERATION Misfolding: ...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 7: NE525 Biology of Neurodegenerative Diseases, Lecture 7
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Proteostasis in PD is disrupted and so the dysfunctional mitochondr...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 4: NE525 Biology of Neurodegenerative Diseases, Lecture 4
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APOPTOSIS: programmed cell death Steps: Condensation of ...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 5: NE525 Biology of Neurodegenerative Diseases, Lecture 5
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Mechanisms of Protein Degradation: Ubiquitin Proteasome Pathway: m...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 10: NE525 Biology of Neurodegenerative Diseases, Lecture 10
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AMYOTROPHIC LATERAL SCLEROSIS (ALS; Lou Gehrigs Disease) Motor neu...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 1: NE525 Biology of Neurodegenerative Diseases, Lecture 1
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Parkinsons, ms, als, huntingtons, prions, alzheimers, FTD, down Dif...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 9: NE525 Biology of Neurodegenerative Diseases, Lecture 9
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ROLE OF HTT IN REST REGULATION HTT sequesters REST in cytosol, les...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 3: NE525 Biology of Neurodegenerative Diseases, Lecture 3
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COMMON FEATURES IN NEURODEGENERATIVE DISEASES: Aggregates: beta she...

Neuroscience
CAS NE 525
Lucia Pastorino
CAS NE 525 Lecture 8: NE525 Biology of Neurodegenerative Diseases, Lecture 8
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Co-Immuniprecipitation technique (2 examples HT and ALS) STUDY: te...

Neuroscience
CAS NE 525
Lucia Pastorino

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