Drugs, Lec 15.docx

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Department
Psychological & Brain Sciences
Course
CAS PS 333
Professor
Barak Caine
Semester
Spring

Description
Drugs, Lec 15:  02/24/2014 Quiz 3:  Most widely prescribed drug: Vicodin (T), Hydrocodone (G), analgesics (clinical classification), opioid (pharmacodynamics). Naloxone reduces the abuse of Suboxone if taken in another way.  Limited maximum effectiveness if why you give buprenorphine.  Most widely used analgesics effect in rats: tail withdrawal. Most widely used test for side effect in rats: IVSA. Intravenous self administration.  Tolerance: rightward shift in the curve.  Clinical therapeutic effect of mu receptor antagonist: rescue from overdose, increase  fertility in women, prevent non­oral abuse of Suboxone.  Why doesn’t Immodium (AD) make you high? Very lipophilic. Loperamide is the generic name. When it goes to GI tract, it sticks to it so much that not  enough will ever reach your bloodstream and make you high.  Oxycontin: sustained release oxycodone pill. opioid analgesic. Sustained release into your GI tract. 
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