BI 433 Lecture Notes - Lecture 4: Gene Expression, Regulatory Sequence, Repressor

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Di erent cell types produce di erent sets of proteins. Cells will need to express di erent sets of genes. Some proteins will be expressed in every cell you encounter. Certain proteins can also only be expressed in certain cells. Certain genes will only be expressed under certain conditions. Human cell expresses 30- 60% of its genome. We will talk at all levels gene expression can be regulated, not just at the transcriptional level. Even undi erentiated, pluripotent cells will express speci c sets of proteins that allow them to maintain an undi erentiated state. Gene expression can be controlled at many levels. Roadmap of what we will talk about today. Central dogma: genetic info in dna is transcribed into mrna copy that rna copy is processed to be exported from cytoplasm. Can be localized to a certain place within the cell mrna has a speci c lifetime.

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