ASL 101 Lecture Notes - Lecture 5: Triglyceride, Intelligent Dance Music, Vasopressin
Document Summary
Diabetes mellitus is a group of metabolic diseases that can be characterized by hyperglycemia that stems from defects in insulin secretion, and/or insulin action (heuther, 2018). The american diabetes society has four classifications of diabetes mellitus; type 1, type 2, other specific types and gestational (heuther, 2018). In type 1 diabetes, the pancreatic beta cells are destroyed, leaving the individual with no insulin. This is usually caused by an autoimmune attack where monocytes and macrophages, and cytotoxic t cells will infiltrate the islets. The insulin reserve that is there will steadily decrease until it"s no longer sufficient enough to maintain a normal blood glucose level in the body (arcangelo, 2018). In type iidm, circulating insulin concentrations increase with the compensation for insulin resistance. The ability for insulin to stop hepatic glucose production and stimulate uptake and use by adipose and muscle cells diminished (arcangelo, 2018). Type ii can occur in the beta cells or the target cells.
