BIOL 303 Lecture Notes - Lecture 23: Archibald Garrod, Friedrich Miescher, Pus

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Replicate- it must be possible to copy the genetic material. Isolated nuclei from white blood cells in pus. Found an acid substance with nitrogen and phosphorus: Man two things in fertilizers are nitrogen and phosphorus. Linked inheritance of inborn errors of metabolism with the lack of particular enzymes. Worked with streptococcus pneumoniae bacteria, which exists in two types: Type s (smooth) = enclosed in a polysaccharide capsule, a slime layer to protect them from the immune system. Termed the conversation of one bacterial type into another as transformation. Enzymes are protein, enzymes produce many phenotypes. Treated lysed 5 bacteria with protease and dnase: Proteases digest proteins, dnase digests dna, rnase digest rna. Used e. coli bacteria infected with with a virus that consisted of a protein head surrounding dna. Grew a batch of virus in a medium containing ^35s (radioactive form of sulfur) And ^32p (phosphorus that radiates regulate activity)

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