GEN-3000 Lecture Notes - Lecture 25: Post-Translational Modification, Methionine, Scrapie
Document Summary
Translation: charged trnas come in, the large and the small ribosome subunits begin separately, elongation. Elongation continues until the ribosome reaches a stop codon , which will be present in the a site. A release factor comes in and cuts at the a site of the ribosome. Genotype and environment impact phenotype: archibald gerrod. Believed there to be a relationship between genotype and proteins. He looked at heritable diseases to determine this: beadle and tatum. Used bread mold to study mutations because. It is easy to grow in a lab. The vegetative form is haploid, which mean that it is easy to see recessive mutations. Their experiments were performed before it became known that dna was the genetic material. They found that exposure to x-rays led to a heritable change in the bread mold spores. They created and characterized nutritional mutants of bread mold spores.
