HLTH-3800 Lecture Notes - Lecture 3: Prospective Cohort Study, Randomized Controlled Trial, Coronary Artery Disease
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Study question for third exam, hlth 380 epidemiology fall 2016. Influenced by whether there are standard diagnostic criteria, the severity of the disease, whether the criteria are subjective/objective. What are the outcomes measures used in cohort studies: discrete events, single events, mortality, first incidence of a disease (incidence, cumulative incidence, ratios, multiple occurrences, of disease outcome (ex: recurrent heart disease, of transitions between states of health/disease. Levels of disease markers: changes in disease markers, rate of change, patterns of growth and/or decline, change in levels over time, ex: effects of aging on disease, transitions of health status (ex: functional disability in elderly) What are the advantages and disadvantages of clinical trials: advantages: medical advances, testing new therapeutic drugs, protects public from dangerous/ineffective drugs, disadvantages: lengthy (~10 years), expensive. Compare and contrast significance tests, p-values, and confidence intervals as measures of effect.
