BC 351 Lecture Notes - Endergonic Reaction, Exergonic Reaction, Activation Energy

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5 Aug 2014
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An enzyme is a biomolecule that catalyzes a specific biochemical reaction. Catalysis is the process of increasing biochemical reaction rates using a molecule (catalyst) not found in the reaction itself. Looking at reactions thinking about electron distribution. You can"t tell anything about reaction rate based on how exergonic or endergonic it is. Transition state intermediate: an activated form of a molecule in which the molecule has undergone partial electron redistribution. Reactants must be activated and gain free energy to reach transition state. Activation energy ( g ) is the energy required to reach the transition state ( ) Looking at forward and backward rates of a reaction can determined keq (roughly) High g - low rate; low g - high rate. They can couple an endergonic reaction to an exergonic reaction, but cannot make an endergonic reaction exergonic. The substrate is the molecule that undergoes the chemical change. This can simply be thought of as the reactant.

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