BC 351 Lecture Notes - C-Terminus, N-Terminus, Protein Folding
Document Summary
The peptide bond is a substituted amide linkage between an -amino group on one amino acid and the -carboxyl of another amino acid resulting in the elimination of water. The covalent bond responsible for holding amino acids together in a protein. The n-terminus is the first amino acid in the protein and the only amino acid with a free -amino group (amino terminus) # of peptide bonds = n -1 n = # of amino acids in the protein. The c-terminus is the last amino acid in the protein and the only amino acid with a free -carboxyl group (carboxyl terminus) The peptide backbone is all atoms in a protein excluding those found in the side chains. Primary (1 ) structure is a description of all covalent bonds linking amino acid residues in a protein. The sequence of amino acids within a protein starting with the n-terminus and ending with the c-terminus.
