Exam 2: Wed Oct 24
Review: Monday in class Oct 22
Quiz Friday Oct 19
α receptors – vasoconstriction (norepinephrine)
β1receptors - ↑ HR, ↑ contractility
β2receptors – vasodilation (epinephrine at low concentration)
Higher concentrations of epinephrine causes vasoconstriction
Veins do not have β r2ceptors – do not vasodilate
3 local factors affecting blood flow?
Active hyperemia: ↑ BF due to ↑metabolism → ↑ metabolites
Reactive hyperemia: ↑ BF following an occlusion of artery
Endothelin is vasoconstrictor
Nitric oxide is vasodilator
EDHF, PGI ar2 vasodilators Myogenic autoregulation is the other major mechanism involved in control locally and we have
discussed it several times.
Pressure changes – autoregulation controls flow
Protects brain, kidney, etc.
Left anterior descending artery – widow maker
Aorta → → → coronary sinus → right atrium but also some draina