BMS 420 Lecture Notes - Vasoconstriction, Endothelium, Arteriole
Document Summary
Reach a certain size cannot move nutrients/waste via diffusion. Co2 transport from cells, o2 transport to cells, nutrient transport, hormone transport (transport of gases and nutrients) Examples of changes in three components of cvs with demand/stress; high altitude; exercise; digestion; sleeping; positional changes. Tone degree of vessel constriction or dilation. Cardiac output systemic = cardiac output pulmonary = venous return (from systemic) = venous return (from pulmonary) Blood flow = blood pressure/resistance aa are higher pressure, resistance than vv. Capillaries are exchange vessels, where diffusion happens, edema (leakage into tissues) Alter blood flow via changes in resistance (tone) Raynaud phenomenon: exaggerated vasoconstriction of digital arteries and arterioles usually due to cold temperatures. Vascular changes cause paroxysmal pallor or cyanosis of digits of feet and hands. Varicose veins, deep vein thrombosis, spider veins, hemorrhoids and more. With deep vein thrombosis, clots can travel to lungs. Poor diastolic filling due to reduced chamber size (walls have thickened) and poor compliance of myocardium.
