Non-competitive antagonism, spare receptor hypothesis

2 Pages
72 Views
Unlock Document

Department
Biomedical Science
Course
BMS 450
Professor
Douglas Ishii
Semester
Spring

Description
13 FebruaryNoncompetitive antagonismBinds to another allosteric site or to the same site irreversiblyNumber of usable receptors decreases with increased noncompetitive antagonistsRemaining receptors are fine so no change in KdPartial agonistsReceptors are fully occupied but there is not a full responseStephenson 1956Spare receptor hypothesisResponse need not be proportional to occupancyefficacykbindingdDRDR inactiveDR a
More Less

Related notes for BMS 450

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit