Calcium efflux, digoxin, Frank-Starling law of the heart, calcium sensitizers, vasodilators, excitation-contraction coupling, angiotensin receptor antagonists, alpha adrenergic antagonists, calcium channel antagonists, nitric oxide, protein kinase G

8 Pages
116 Views
Unlock Document

Department
Biomedical Science
Course
BMS 450
Professor
Douglas Ishii
Semester
Spring

Description
19 AprilDecrease calcium effluxInhibition of the NaCa exchanger decreases calcium effluxGood NaCa exchange inhibitors are not availableLimit NaCa exchanger function indirectlyCardiac glycosidesExample digoxinDigoxinAka digitalis is a purified cardiac glycoside extracted from the foxglove plant Digitalis lanataDigitalis has been used for centuries to treat heart conditionsCardiac glycosides digoxinInhibit the NaK ATPaseLowers intracellular potassiumIncreases intracellular sodiumNaCa exchangerActivity is regulated solely by the concentration of sodium and calcium sodium in the cell willcalcium efflux through the exchangerFrankStarling law of the heartThe heart pumps what it receivesStretching the myocardium with increased preload increase the force of contractionHeart receives more blood it pumps harderStretching the myocardium to increase force of contraction has its limits
More Less

Related notes for BMS 450

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit