BMS 460 Lecture Notes - Spermatogenesis, Dehydroepiandrosterone Sulfate, Vas Deferens
Document Summary
Benign adenomas are not recognized clinically (as they may be discarded in the menstrual blood); if they present, they are indistinguishable from endometrial hyperplasia. Hyperplastic glands may be with or without atypia; atypia may progress to adenocarcinoma. 25% - 30% of women with complex hyperplasia may progress to atypia or adenocarcinoma. Estrogen-induced hyperplasia and neoplasia might be related to the inactivation of a tumor suppressor gene, pten (phosphatase and tensin homologue) Stage ii carcinoma extending into cervix and invading myometrium. Stage iii tumor extending through wall of the uterus but not outside. Stage iv carcinoma infiltrating the bladder or extending outside of pelvis. Sex cord stromal cell origin granulosa cell tumor. Prophylactic oophorectomy and salpingo-oophorectomy in high risk women. Breast consists of cells and tissues that respond to hormones. Each age group of women is affected by different breast diseases. The functional status of the breast predisposes this organ to different diseases, e. g. , mastitis.