BMS 460 Lecture Notes - Vasoactivity, Basophil, Elastase
26 Apr 2014
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Swollen mitochondria and rer, nuclear clumping, ruptured cell membrane. Can be caused by receptor/ligand, injury, withdrawal of growth factors/hormones, &c. Loss of plasma membrane"s ability to maintain electrochemical gradients, which results in. Influx of ca2+ ions and dysfunction of mitochondria, and. The general tissue architecture of coagulative area is preserved for weeks because of rapid inactivation of cellular hydrolytic enzymes. Manifestations of coagulative necrosis are the same regardless of the cause of cell death. Dead cells acidic ph activates lysosomal enzymes liquefaction; occurs most often in the brain. When dissolution of dead cells occurs rapidly because of liquefied area of lysosomal enzymes; an abscess or cyst may form. Death of adipose tissue; usually results from trauma or pancreatitis (release of digestive enzymes) Dry gangrene is a form of coagulative necrosis characterized by blackened, dry, wrinkled tissue that is separated from adjacent healthy tissue.
