Skeletal muscle structure, basal lamina, innervation ratio, motor unit properties

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Health + Exercise Science
HES 319
Brian Tracy

24 March Relaxation causes by resequestration of calcium in SR Tetanic force caused by lack of time – all calcium cannot be resequestered between twitches Pumps cannot keep up with release Classical model – all force of muscle applied at end where it connects to tendon Skeletal Muscle Structure The contractile filaments (actin, myosin) are supported by a complex array of structural proteins that serves to transmit the force of the sarcomere to the tendon. These proteins are ubiquitous (everywhere), provide scaffold, transmit force to outside of cell Titin – elastic molecule From Z line to myosin Costamer – junction between sarcolemma and Z lines Also known as focal adhesion Protein complex including dystrophin Integrins cross sarcolemma, connect to basal lamina Integrins link the extracellular matrix and cytoskeleton at focal contacts. Focal contacts are dynamic structures dete
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