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Chapter 8 Life 102.docx

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Life Science
LIFE 102

Chapter 8 Life 102 • ATP drives endergonic reactions by phosphorylation, transferring a phosphate group to some other molecule such as a reactant • This recipient molecule is now phosphorylated • ATP is a renewable source that is generated by addition • The energy of phosphorylated ADP comes from catabolic reactions in the cell • The chemical potential • The catalyst is a chemical agent that speeds up a reaction without being consumed by the reaction • An enzyme is a catalytic protein • Hydrolysis of sucrose by the enzyme sucrose is an example of an enzyme-catalyzed reaction. • SUCRASE the ending in a molecule means it is an enzyme • Every chemical reaction between molecules involves bond breaking and bond forming • The initial energy needed to start a chemical reaction is called the free energy of activation or (EA) • Activation energy is often supplied in the form of heat from the surroundings • Squiggly lines an ordinary covalent bond that is being strained and it makes it easier for them to break • Enzymes catalyze reactions by lowering the EA barrier • The reactant that an enzyme acts on is called a substrate • The enzyme binds to its substrate, forming an enzyme substrate complex • The active site is the region in the enzyme where the substrate binds • Induced fit of a substrate brings chemical groups of the active site into positions that enhance their ability to catalyze the reaction. • In
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