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Cell cycle, mitosis, cytokinesis, cell cycle control

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Colorado State University
Life Science
LIFE 210
Paul Laybourn

28 November Each cell cycle produces two genetically identical daughter cells The only way to make a new cell is to duplicate a cell that already exists. Cell cycle: the cycle of cell growth, duplication of its contents, and division The most fundamental task is the passing of its genetic information to the next generation of cells. The major events of the cell cycle Chromosome duplication occurs during S phase, ~12 hours in mammalian cell Chromosome segregation and cell division occur in M phase, 1 hour M phase → nuclear division + cytoplasmic division The stages of nuclear division (mitosis) and cell division (cytokinesis) In prophase DNA molecules are disentangled and condensed into sister chromatids. Nuclear envelope disassembly → sister chromatids attach to the spindle (giant array of microtubules) Anaphase: sister chromatids align at the spindle equator and separate Telophase: packaging into separate nuclei The eukaryote cell cycle is divided into four phases Time to double the mass of proteins and organelles > time to duplicate chromosomes and divide G 1hase + S phase + G phas2 = interphase (23 hours) The cell monitors conditions before committing to S phase/mitosis (G phase). 0 Start point Cell cycle control is simila
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