Each cell cycle produces two genetically identical daughter cells
The only way to make a new cell is to duplicate a cell that already exists.
Cell cycle: the cycle of cell growth, duplication of its contents, and division
The most fundamental task is the passing of its genetic information to the next
generation of cells.
The major events of the cell cycle
Chromosome duplication occurs during S phase, ~12 hours in mammalian cell
Chromosome segregation and cell division occur in M phase, 1 hour
M phase → nuclear division + cytoplasmic division
The stages of nuclear division (mitosis) and cell division (cytokinesis)
In prophase DNA molecules are disentangled and condensed into sister chromatids.
Nuclear envelope disassembly → sister chromatids attach to the spindle (giant array of
Anaphase: sister chromatids align at the spindle equator and separate
Telophase: packaging into separate nuclei
The eukaryote cell cycle is divided into four phases
Time to double the mass of proteins and organelles > time to duplicate chromosomes
G 1hase + S phase + G phas2 = interphase (23 hours)
The cell monitors conditions before committing to S phase/mitosis (G phase).
Cell cycle control is simila