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Class Notes for Microbio, Immun, Pathology at Colorado State University

Exam Study Guides for Microbio, Immun, Pathology Courses

Covers all exam topics.

MIP 342 Lecture Notes - Lecture 1: B Cell, Chemotaxis, Mycobacterium

Ch.1 part 3 – notes cont’d  2ndary immune response o Previously seen pathogen attacks again o AB already there from first time o Memory B and T cells from first exposure recognize ...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Intracellular Parasite, Immunoglobulin G, Tumor Necrosis Factor Alpha

27 MarchQuick Vocabulary ReviewNave T cell mature out of the thymus circulating has not seen antigenEffector T cell capable of mediating an immune response has been activatedMemory T cell longlived capable of rapid and rob...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Cell Adhesion Molecule, Regulatory T Cell, Granulocyte Macrophage Colony-Stimulating Factor

29 AprilThe big pictureTumors formed from cancer cellsUnregulated rapid growth of host cellsOften dedifferentiatedAltered protein expressionImmune system eliminates most cancer cellsCD8 CTLs NK CD4 TcellsRecognize altered ...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Thoracic Duct, Eosinophil, Wound Healing

25 JanuaryInnate immune responseRecognizes broad classes of antigensInbuilt immunity to resist infectionPresent from birthNot antigenspecificNot enhanced by second exposureHas no memoryUses cellular and humoral componentsI...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Polio Vaccine, Meningococcal Disease, Smallpox

26 AprilHepatitis B vaccineFirst vaccine give can be as early as 1 moth after birthNo adverse side effectsvery safe vaccineHepatitis BNot a problem for normally functional immune systemProblematic 3 years liver cancerSalk ...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
Innate immune system receptors, signaling, innate response, innate-like lymphocytes, oxidative burst, cytokines, GPCR, sepsis

30 JanuaryWhat do I need to know Innate Immune System ReceptorsHow do the cells and molecules of the innate response recognize and attack broad classes of pathogensHow do white blood cells get to tissues to attack pathogen...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Alkylation, Antitoxin, Rubella Virus

24 AprilWhy no effective vaccine for HIV yetHIV uses immune receptors CD4 and cytokine that are needed by immune systemHigh mutation rate of HIV RT is sloppyHIV may be latent for years before causing AIDSHIV may be encount...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Interleukin 4, Antigen, Cd19

29 MarchAPC presents antigen costimulates T0 nave CD4 T cellHIL6TGFdifferentiates into T17IL17HIL12IFNdifferentiates into T1HIFNIL2stimulates B cellIgG2aIFNIL2stimulates CD8 T celldifferentiates into CTLIFNhyperstimulates ...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Red Pulp, Mycobacterium Leprae, Bone Marrow

28 JanuaryLag phase between exposure and response710 daysB cells make antibodiesBCR T cells use the TCR conserved structures for antigen recognitionB cells have B cell receptorantibody attached to cell membraneVariable reg...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Tradd, Cd28, Chromatin

25 FebruaryTCR signalingKinases happenPLC is activated by Itk and cleaves phosphatidylinositol bisphosphate PIP to yield diacylglycerol DAG and inositol trisphosphate IPIP 2332increases intracellular Ca concentration activ...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Retrovirus, Antigen, Nucleoside

22 AprilAIDSInfectionFlulike disease 5080 of cases 26 weeksAsymptomatic phasemean of 10 yearsSymptomatic phaseinfections that show in immunocompromised patientsAIDSif untreated death within 1 yearReemergence of Tuberculosi...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Growth Factor, Lck, Interleukin 5

22 February T cell receptors antibody B cell receptorsT cell receptors all use VDJ recombinationMHC molecules do notChapter 7 Signaling part 2What do I want you to knowDont panicVery easy concept will be on the testKINASES...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Antigen Presentation, B Cell, Chromosome

20 FebruaryWhat pathway processes live viruses exclude DC cross presentationExogenous and endogenous pathways depending on virus locationFunctional MHC Class I genesHuman HLAA HLAB HLACMouse H2K H2D H2LFunctional MHC Class...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Bruton'S Tyrosine Kinase, Thymus, Meningococcal Disease

19 AprilThe big picture Lessons about the immune system from immunodeficiency diseasesNaturally occurring immunodeficiency diseases teach us about the role of different parts of the immune system in defense against pathoge...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel
MIP 342 Lecture Notes - Respiratory Tract, Humorism, Defensin

23 JanuaryCourse Overview Where are we goingChapter 1 Overview of the whole course very useful but detailedDr SchenkelBuilding blocks of Immunology and nomenclatureChapters 27Complement Dr ZabelDr MichelHow does the innate...

Microbio, Immun, Pathology
MIP 342
Alan Schenkel

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