Class Notes for Microbio, Immun, Pathology at Colorado State University (CSU)

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CSUMIP 342Alan SchenkelSpring

MIP 342 Lecture Notes - Intracellular Parasite, Immunoglobulin G, Tumor Necrosis Factor Alpha

OC2547364 Page
11 Jul 2014
37
Na ve t cell: mature (out of the thymus), circulating, has not seen antigen. Effector t cell: capable of mediating an immune response, has been activat
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CSUMIP 342Alan SchenkelSpring

MIP 342 Lecture Notes - Thoracic Duct, Eosinophil, Wound Healing

OC2547367 Page
11 Jul 2014
28
Also involved in the triggering and amplification of adaptive immune responses. Antibodies reflect infections to which an individual has been exposed d
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CSUMIP 342Alan SchenkelSpring

MIP 342 Lecture Notes - Antigen Presentation, B Cell, Chromosome

OC2547363 Page
11 Jul 2014
50
Exogenous and endogenous pathways, depending on virus location. Human hfe (iron metabolism), hla-e (recognize by nk), hla-g (prevents nk attack in plac
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CSUMIP 342Alan SchenkelSpring

MIP 342 Lecture Notes - Immunoglobulin A, Cytotoxicity, Peristalsis

OC25473610 Page
3 Jul 2014
35
Exaggerated immune response to innocuous antigens that can cause damage to the individual. A hypersensitivity reaction that can include hay fever, asth
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CSUMIP 300Erica SuchmanSpring

MIP 300 Lecture Notes - Eukaryotic Transcription, Cistron, Precursor Mrna

OC2547362 Page
1 Jul 2014
31
Flow of information: dna rna (transcription) protein (translation) Transfer trna carries amino acids to ribosome during translation. Messenger mrna, co
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CSUMIP 300Erica SuchmanSpring

MIP 300 Lecture Notes - Immunoglobulin M, Opsonin, Streptococcus

OC2547363 Page
27 Jun 2014
43
How specific ones become plasma cells and make antibodies. Phagocytic cell eats antigen expresses antigens (with multiple epitopes) on cell surface wit
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CSUMIP 342Alan SchenkelSpring

MIP 342 Lecture Notes - Retrovirus, Antigen, Nucleoside

OC2547364 Page
11 Jul 2014
26
Flu-like disease (50 80% of cases) - 2 6 weeks. Symptomatic phase infections that show in immunocompromised patients. Aids if untreated, death within 1
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CSUMIP 342Alan SchenkelSpring

MIP 342 Lecture Notes - Bruton'S Tyrosine Kinase, Thymus, Meningococcal Disease

OC2547367 Page
11 Jul 2014
25
The big picture: lessons about the immune system from immunodeficiency diseases. Naturally occurring immunodeficiency diseases teach us about the role
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CSUMIP 342Alan SchenkelSpring

MIP 342 Lecture Notes - Respiratory Tract, Humorism, Defensin

OC2547363 Page
11 Jul 2014
30
Chapter 1: overview of the whole course: very useful but detailed! The adaptive response: how specific immune responses are made. Chapter 8: how b and
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CSUMIP 342Alan SchenkelSpring

MIP 342 Lecture Notes - Influenza A Virus Subtype H3N2, Trigeminal Ganglion, Mhc Class I

OC2547364 Page
11 Jul 2014
34
Antigenic variation (now you see it now you don"t) Molecular mimicry (do as i say not as i do mainly large dna viruses, downregulate or prevent immune
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CSUMIP 342Alan SchenkelSpring

MIP 342 Lecture Notes - Antigen Processing, Tlr 1, Neutrophil

OC2547363 Page
11 Jul 2014
30
Only 3 types of immune cells can activate na ve t cells. B cells mostly when antigen levels are low. Toll-like receptors (means a pathogen is present)
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CSUMIP 342Alan SchenkelSpring

MIP 342 Lecture Notes - Cytidine Deaminase, Cytidine, Somatic Hypermutation

OC2547362 Page
11 Jul 2014
22
Nucleotide additions by tdt must be in-frame or premature termination and death of cell results. Gene conversion - rare, long slow process except in bi
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