MIP 300 Lecture Notes - Dengue Fever, Spasticity, Escherichia Coli
27 Jun 2014
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Document Summary
Proteins, made by gram + and gram . E. g. botulism inhibits stimulatory neurotransmitter release from nerves, no nerve impulses, flaccid paralysis. Tetanus inhibits inhibitory neurotransmitter release from nerves, constant nerve impulses, spastic paralysis. E. g. cholera, e. coli, stop h2o uptake in intestines, diarrhea. E. g. diphtheria, shigella (food borne illness), anthrax inhibit protein synthesis. Superantigens overstimulate the immune system, cause similar response to. Staphylococcus aureus tsst1 (toxic shock syndrome toxin 1) endotoxins. Genes: chromosomal, plasmids, phage: coli plasmid. Diphtheria lysogenic phage (integrated into the genome) Cause an immune response make antibodies specific for the toxin called antitoxins. Toxins used to make vaccines heat inactivated toxins: toxoids (after symptoms) Can inject people with antitoxins past exposure antiserum or antitoxin. Causes fever, shock, decreased blood pressure, cold, faint, blood coagulation, weakness, inflammation, intestinal hemorrhage, diarrhea. Innate immunity general barriers, physical barriers, chemical barriers, biological, inflammation, fever. Acquired immunity humoral branch (b cells and antibody), cell mediated branch (t cells)
