Clonal selection, secondary immune response, microbe's response, HIV infection

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Department
Microbio, Immun, Pathology
Course
MIP 300
Professor
Erica Suchman
Semester
Spring

Description
22 FebruaryWhats happening during the primary response lag periodClonal selectionThousands of immature BcellsHow specific ones become plasma cells and make antibodiesClonal selection Tcell dependent antigen activationPhagocytic cell eats antigenexpresses antigens with multiple epitopes on cell surface with MHC class II moleculesImmature TH recognizes specific epitope on antigenMHC II complexphagocytic cell releases growth factors interleukines and cytokines TH becomes mature activated dividesCreate many mature TH cells specific for the same epitope on the antigenImmature Bcell surface IgM binds antigenmature TH binds specific epitope on antigenMHC II complex on immature Bcell surface releases growth factors that activ
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