ITP, hemostasis, role of endothelial cells, coagulation, clot retraction, clot dissolution, hemophilia A, DIC, heart

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Department
Microbio, Immun, Pathology
Course
MIP 315A
Professor
Gerald Callahan
Semester
Spring

Description
1 MarchExam next ThursdayLymphomasleukemias will not be on the examObjectives Lecture 12Understand the basic mechanisms of coagulationKnow the genetics symptoms and effects of hemophiliaUnderstand the pathogenesis and symptoms of ITP and DICITPMaking antibody against own plateletsReduced number of plateletsThrombusblood clotHemostasisStepwise process to stop bleedingThree major componentsVascular wallPlateletsCoagulation cascadeVascular spasmPlatelet plugFibrin clotClot retractiondissolutionRole of Endothelial CellsNormally inhibit coagulation by actively inhibiting platelet adherenceAfter injury of inflammation release procoagulant proteins
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