MIP 315A Lecture Notes - B Cell, Immunodeficiency, Retrovirus
16 May 2014
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Document Summary
Know the organs and the cells of the immune system. Understand how t cells and b cells protect against infection. Primary lymphoid organs thymus & bone marrow. Secondary lymphoid organs sites of immune response, lymph nodes, &c. B cells, t cells, macrophages & dendritic cells. T cells capable of initiating immune response when find invaders. Mhc molecules pick up antigen, break it up, display it. Once the t cell recognizes it, lots of processes begin. Antigen shows up, processed t cells arrive, find antigen b cells arrive b cells proliferate and specialize. Every virus that infects a cell has to use a specific molecule to bind to another specific molecule on a cell. Antibodies cover the virus so it can"t bind. Gives traction so the invader can be eaten. Antibodies are too big to get inside cells. Deals with intracellular infected cells are killed by t cells. After b cell reacts with t cell / invader, b cell plasma.
