MIP 315A Lecture Notes - Rheumatoid Arthritis, Lipopolysaccharide, Blood Pressure

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Antibodies & antigens can link into a big complex and becomes no longer soluble. Large amount of pre-existing antibody + large amount of antigen. Can lead to anaphylaxis inflammation caused by an immune event. Cd8+ cells activated, find cells presenting altered protein and destroy them. Didn"t really pose a threat, but the immune system thinks it did. Includes at least type ii & iii hypersensitivities. Hard to categorize some hypersensitivities since several symptoms can be present at once. Systemic inflammatory disease affecting 2 million people in the united states. Results in average of 5 to 10 years decrease in life expectancy. Type ii since it"s antibodies against own antibodies. Most commonly affects joints in fingers, ankles, & knees. Understand the nature of the science of pathology. Know the leading causes of death in the u. s. Know the leading causes of death in the underdeveloped world. Understand the nature and function of the normal flora.

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