Class Notes (859,693)
US (334,322)
CSU (3,049)
MIP (104)
MIP 342 (39)
Lecture

Antibodies, toxin neutralization, venoms, blocking of viral infection/bacterial adhesion, classic complement pathway, Fc receptors

4 Pages
27 Views

Department
Microbio, Immun, Pathology
Course Code
MIP 342
Professor
Alan Schenkel

This preview shows page 1. Sign up to view the full 4 pages of the document.
Description
3 AprilAntibiodies Neutralize Bacterial ToxinsMany toxins have 2 domainspartslock and key section to get in toxic sectionAntibody binds to section that binds to cellToxin binds to cellular receptorsendocytosis of toxinreceptor complexesdissociation of toxin to release active chain which poisons cellAntibody protects cell by blocking binding of toxinIgA important at mucosa and IgG important within blood and tissuesVenomsCan be extremely toxic and deadlyOften very fastacting no time for adaptive immunity to make antibodies against itPassive immunization is the only solutionA small amount of venom is injected into the horsesheep to elicit an antibody responseThe antivenom antibody is then harvested from the horse and injected into bitten humansdogsAntibodies Block Viral InfectionViruses are tropic for specific tissues based on the presence of particular cell surface receptorsAntibodies directly bind to viral receptorbinding proteinsVirus binds to receptors on cell surfacereceptormediated endocytosis of virusacidification of endosome after endocytosis triggers fusion of virus with cell and entry of viral DNAAntibody blocks binding to virus receptor and can also block fusion eventAntibodies Block Bacterial AdhesionBacteria have adhesins
More Less
Unlock Document
Subscribers Only

Only page 1 are available for preview. Some parts have been intentionally blurred.

Unlock Document
Subscribers Only
You're Reading a Preview

Unlock to view full version

Unlock Document
Subscribers Only

Log In


OR

Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit