B cell maturation, membrane enclosed vesicles, pathogen recognition, antigen processing, immunoproteasomes, major histocompability

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Department
Microbio, Immun, Pathology
Course
MIP 342
Professor
Alan Schenkel
Semester
Spring

Description
18 FebruaryCD4 helper T cells binds to MHC class IIVregion assemblysomatic recombination of DNA irreversible change occurs in B and T cellsJunctional diversityimprecise joining Nsequence insertion in DNA irreversible change occurs in B and T cellsSwitch recombination class switchingsomatic recombination of DNA irreversible change occurs in B cellsSomatic hypermutationDNA point mutation irreversible change occurs in B cellsIgM IgD expression on surfacedifferential splicing of RNA reversible and regulated change occurs in B cellsMembrane vs secreted formsdifferential splicing of RNA reversible and regulated change occurs in B cellsChapter 6 What do I want you to knowEndogenous antigensinside shown to CD8sExogenous antigensoutside phagocytosed and shown to CD4How are MHC proteins organized and have diversitySuperantigenshow do they workDistinct membrane enclosed vesicles in cellsSecretory vesicleCytosolNucleusPhagosome or endosomeLysosome low pH proteasesGolgi apparatus
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