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MIP 300 Lecture Notes - Gamma Globulin, Immunoglobulin G, Immunoglobulin A

Microbio, Immun, Pathology
Course Code
MIP 300
Erica Suchman

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20 February
Immune response
Nonspecific barriers (last lecture)
These are all referred to as the innate immune response, which is non-specific,
i.e. it protects against all microbes, not a specific microbe
Specific immunity (4 types)
Naturally acquired
Active: from infection
Lifetime – chicken pox
Few years – tetanus
Passive: from mother through placenta, milk
Weeks to months
Note: why infants given PCR HIV test (looks for viral DNA in cells)
Not ELISA (looks for antibodies against virus)
Mother HIV + ELISA, so is baby even if no virus
Can’t test for antibodies in baby since they could be the mother’s
Artificially acquired
Active: from vaccine (before contact)
Lifetime – smallpox?, Hep B
Few years – tetanus
Vaccines that do not last long are boostered
Depends on how strong an immune response vaccine induces
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