MIP 300 Lecture Notes - Gamma Globulin, Immunoglobulin G, Immunoglobulin A

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These are all referred to as the innate immune response, which is non-specific, i. e. it protects against all microbes, not a specific microbe. Note: why infants given pcr hiv test (looks for viral dna in cells) Mother hiv + elisa, so is baby even if no virus. Can"t test for antibodies in baby since they could be the mother"s. Vaccines that do not last long are boostered. Depends on how strong an immune response vaccine induces. Passive: from gamma-globulin shots (aka antiserum) antibodies against the microbe or antitoxin antibodies against toxin. T-suppressor (ts): ? suppress function of other lymphocytes. Antigens may have more than 1 epitope which elicits lymphocyte response. Iga: serum, secretions (intestines, respiratory, reproductive tracts, breast milk) Igm: serum, 1st antibody produced, surface of b-cells (receptor) Opsonization attracts phagocytic cells, increases rate of phagocytosis. Proteins that bind to antibodies and kill bacteria, protozoa, fungi, enveloped viruses by lysis. Complement proteins bind antibody, pop holes in membranes.

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