SOCR 330 Lecture Notes - Chromatin, Phoebus Levene, Deoxyribonuclease

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1 Apr 2014
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Human studies compare traits in identical and fraternal twins. Mz twins have more similar uterine environment than dz (often share membranes) Mz twins often treated more similarly by parents and teachers. Dz twins of different sexes treated more differently than twins of same sex. Dna (deoxyribonucleic acid) first isolated from lymphocyte nuclei in pus-filled bandages i n1868 by miescher. Eukaryotic chromosomes known since late 1800s to contain both dna and protein ( chromatin ) Chemist phoebus levene observed in 1910 that dna contains equal amounts of four nucleotides. For decades scientists dismissed dna and concentrated on proteins as the genetic material. Three key experiments solved the mystery of what molecule carries genetic information: Found transforming agent from griffith"s 1928 experiment was not destroyed by protease or rnase.

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