Randon and non-random mating, inbreeding

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Colorado State University
Soil + Crop Sciences
SOCR 330
Sarah Ward

18 November Random and Non-Random Mating Random mating Any one genotype equally likely to pair with any other genotype in population Negative assorted mating Dissimilar genotypes pair Positive assorted mating Similar genotypes pair Inbreeding Mating pair more closely related than two individuals drawn at random from population Increased probability of homozygosity for deleterious alleles (inbreeding depression) Probability that offspring from first cousin mating has two copies of single allele identical by descent is 1/16 Closed loops on pedigree indicate inbreeding Detecting Inbreeding As a Deviation from Hardy-Weinberg Equilibrium Two alleles with incomplete dominance control flower color AA = red Aa = pink aa = white Geneticist counts 100 plants and finds 12 white-colored ones Next year counts 100 plants again and finds 19 pink-flowered ones Is population in Hardy-Weinberg equilibrium? Quantifying Inbreeding The breeding coefficient F measures t
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