BIO 1400 Lecture Notes - Lecture 2: Phosphodiester Bond, Pyrimidine, Purine

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12 Feb 2018

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There are four different nucleotides, four different building blocks. The phosphate group is always the same whether its dna or rna. Nitrogenous bases are either double ring structures (purines) or single ring (pyrimidines) The sugar phosphate backbone of the two two polynucleotides are on the outside of the helix. The variation in the backbone comes from the bases. Each phosphate group in the backbone has a negative charge. Dna or rna an entirely negative charge making it polar. Nucleotides are negatively charged because of the phosphate group. Every nucleotide bears a negative charge so the dna and rna are highly polar. Condensation/dehydration reactions: a molecule of water is stripped from the 2 monomers (together) and thus is formed. The 2 monomers are now connected by a covalent bond: in each polymer, the covalent linkage between the monomers gets its own name. In nucleic acids, the bond is called a phosphodiester bond.

Related Questions

1. Unlike DNA, RNA contains

deoxyribose

a double strand

phosphates

uracil

Nucleic acid structure

2. In transcription, uracil will bond with:

thymine

cytosine

adenine

guanine

Transcription

3. The first team of scientist to document the structure of DNA was:

Franklin and Wilkins

Watson and Crick

Pauling and Chargoff

None of the above

DNA structure

4. Organelles that synthesize protein are:

lysosomes

ribosomes

endoplasmic reticulum

golgi bodies

5. Most of the time in a cell's life, it's DNA is in the form of:

Chromatin

Chromatids

Replicated chromosomes

Spindle fibers

6. Uracil is a nitrogen base that pairs with adenine. Using this information, one could conclude that uracil is a:

Purine

Pyrimidine

Neither a purine or pyrimidine

Not enough information

7. a nucleotide does not consist of a:

polymerase

5-carbon sugar

phosphate group

nitrogen base

8. The genetic code in DNA of an individual depends on the sequence (order) of:

nucleotides

purines only

phosphates

sugars

9. Before a cell divides, it must duplicate its DNA in a process known as:

translation

transformation

transcription

replication

10. The basic unit (building block) of a protein is a (an):

carbohydrate

amino acid

lipid

hydrogen bond

11. Unlike DNA, RNA contains:

deoxyribose

a double strand

phosphates

uracil

12. The structure of DNA was first documented in:

1945

1953

1956

1962

13. In DNA replication, the new molecules produced are:

of unequal length

both assembled in the same direction

built with purines as the backbone

assembled in opposite directions

DNA replication

14. The "backbone" of DNA is composed of:

ribose and phosphates

deoxyribose and phosphates

ribose and uracil

deoxyribose and thymine

DNA structure

15. RNA differs from DNA in which of the following ways?

RNA is single-stranded

RNA contains ribose

RNA does not contain thymine

All of the above

DNA structure

16. Which of the following is NOT required for the transcription process itself?

RNA polymerase

DNA

uracil-containing nucleotides

ribosomes

skyhamster121

QUESTION 1. Compared to eukaryotic genomes, only prokaryotic genomes:

A. contain DNA organized by histones.

B. contain usually one, circular chromosome.

C. contain plasmid DNA.

D. have chromosomes contained in a nucleus.

QUESTION 2. Azathioprine is a drug that may be prescribed to transplant recipients to reduce the chance of tissue rejection reactions. In its active state, it acts as a purine analogue, inhibiting DNA biosynthesis. This means that 6-mercaptopurine will be inserted in place of a purine containing nucleotides during DNA replication. Given this drug's mode of action, you would expect it to be incorporated into DNA in place of:

A. nucleotides containing guanine or cytosine.

B. nucleotides containing adenine or thymine.

C nucleotides containing adenine or guanine.

D. nucleotides containing guanine nucleotide or uracil.

QUESTION 3. RNA is distinguished from DNA because only RNA:

A. typically exists as a single-stranded molecule.

B. has a 3' to 5' directionality.

C. is composed of nucleotides that contain the sugar deoxyribose.

D. is composed of nucleotides that contain the nitrogen bases T, C, G, and A.

QUESTION 4. How are RNA nucleotides different from DNA nucleotides? To be marked correct, you'll need to select all true statements, as there may be more than one correct answer.

A. RNA nucleotides do not contain thymine.

B. RNA nucleotides use the sugar ribose, while DNA nucleotides do not.

C. RNA nucleotides lack phosphate.

D. RNA nucleotides incorporate pyrimidine nitrogen bases, while DNA nucleotides only incorporate purine nitrogen bases.

2. Inductive reasoning in science:

a) is often part of the discovery process

b) proceeds from specific observations to general conclusions

c) is complementary to deductive reasoning

d) often relies on descriptive science

e) all of the above

3. A proton is a subatomic particle with:

a) a negative charge and an atomic mass of 1

b) a negative charge and a negligible mass

c) a positive charge and an atomic mass of 1

d) no charge and an atomic mass of 1

e) no charge and a negligible mass

4. Nonpolar covalent bonds are formed when:

a) electrons are shared equally by atoms

b) electrons are shared unequally by atoms

c) electrons are transferred completely from one atom to another

d) two atoms both lose electrons

e) a negative pole of one atom is attracted to a positive pole of another atom

5. Hydrogen bonds are formed when:

a) electrons are shared equally by atoms

b) electrons are shared unequally by atoms

c) electrons are transferred completely from one atom to another

d) two atoms both lose electrons

e) a negative end of one molecule is attracted to a positive end of another molecule

6. Compared with a solution of pH = 4, a solution with pH = 6 is:

a) 2 times less acidic

b) 10 times more acidic

c) 100 times more acidic

d) 10 times less acidic

e) 100 times less acidic

7. Nucleotides are formed from:

a) 3 fatty acids and a glycerol

b) 3 monosaccharides and a glycerol

c) a fatty acid, a pentose sugar, and 1 or more phosphate groups

d) a nitrogenous base, a pentose sugar, and 1 or more phosphate groups

e) an amino acid, a pentose sugar, and 1 or more phosphate groups

8. Which nucleotide base is found in RNA, but not in DNA?

a) adenine

b) cytosine

c) guanine

d) thymine

e) uracil

9. The correct sequence for the levels in the taxonomic hierarchy is:

a) domain â class â order â kingdom â phylum â genus â family â species

b) kingdom â domain â class â phylum â order â family â genus â species

c) domain â kingdom â phylum â class â order â family â genus â species

d) domain â kingdom â phylum â class â order â genus â family â species

e) phylum â kingdom â domain â order â class â genus â family â species

10. The outer (valence) shell of an atom can hold a maximum of:

a) 4 electrons

b) 6 electrons

c) 8 electrons

d) 12 electrons

e) 18 electrons

11. Which of the following is not true of lipids?

a) they are a diverse group of biological molecules

b) they are hydrophobic

c) they are less oxidized than carbohydrates

d) they are strongly polar

e) they can store more energy than carbohydrates

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BIO 1400 Lecture Notes - Lecture 2: Phosphodiester Bond, Pyrimidine, Purine

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