BIOG 1440 Lecture Notes - Lecture 3: Cell Membrane, Lipid Bilayer, Facilitated Diffusion

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Osmosis: diffusion of free water across a selectively permeable membrane, like a plasma membrane: more technically, movement of solvent across a selectively permeable membrane into a region of higher solute concentration, solvent=water; solute=basically anything else ii. Problems associated with osmosis: tonicity: the ability of a surrounding sol"n to cause a cell to gain or lose water. Isotonic solution: solute concentration is the same as that inside. Cells with strong walls more resistant to hypotonicity: hypotonic plant cells normally swollen (turgid) Structural evidence for alternating access hypothesis: energy is used to drive structural changes which allow transport against a concentration gradient, no atp, protein exists in either open or closed configurations. In the presence of a modified form of atp (amppnp) the protein is mostly in outward configuration: active transport is also used to drive ion transport. Sodium-potassium pump is one type of active transport system.

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