BIOMI 2900 Lecture Notes - Lecture 5: Mycoplasma Genitalium, Gram Staining, Dna Gyrase
1 Sep 2017
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Can transport even despite low external concentrations: coli has one. Methanogen has one (horizontal transform) from bacteria, to bind k. Pts system (active transport: coli uses for glucose. Abc transporters also used to pump anti-cancer drugs out of tumor cells. Energy from phosphate bond in pep is used for other reactions. Dna in eukarya (includes material not in text or in the text, but not in the readings) Dna put together in such away that there are no ribosomes inside nucleoid. Chromosomes - typically 2-6 mb (million bases) long. Also circular (mostly: coli (4. 5 mb) would be 1. 5 mm long if stretched out. Dna is supercoiled (so that it fits in the cell) Dna gyrase - puts a nick/gap in a strand, coils it, then connects it again. Have to be a lot of positive ions (k+, mg2+, amines, +charged) Since dna is negative (phosphate group etc. ) Rapidly-growing e. coli cell contains ~20,000 ribosomes and > 2,000,000 proteins.
