NS 1160 Lecture Notes - Lecture 2: Ghrelin, Gastrin, Peristalsis
7 Sep 2016
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Document Summary
A series of steps used by scientists to explain cause and effect relationships. Strengths: double-blind, placebo-controlled, randomized, simulate real life, large sample, wider age/gender/bmi range, generalizability, straightforward message. Weakness: unmeasured parameters, drop-out rates, small sample size, highly specific population, short study duration. Food stimuli: senses that makes you excited for food. Epiglottis: small flap of elastic cartilage tissue that covers the trachea when swallowing food. Food bolus stimulates touch receptor cells in the back of the throat. Peristalsis carries food down the esophagus and through the rest of the gi tract. Normally constricted, relaxes on contact with food to allow it to enter stomach. Voluntary control due t innervation from the pns. Mucous: released in cephalic phase and protects the stomach tissue from acids. Hcl: release triggered by release of gastrin; breaks down the bolus. Pepsinogen: converted to pepsin by hcl, breaks down proteins. Ghrelin: secreted by empty stomach and stimulates eating. Intrinsic factors: required for the absorptions of b12.
