BIOL 202 Lecture Notes - Lecture 9: Phagocytosis, Tetanospasmin, Plasma Cell

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23 Apr 2017

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Chapter 21: resistance and the immune system (adaptive immunity) There could be many different antibodies that fight the same antigen. Adaptive immune response: adaptive immunity, specific: antigenic determinants similar to epitopes, tolerance of self, minimize damage and targeting of its own molecules, minimizing cytokine storm, immunological memory, antigens remember the antibodies that were sent out. Specificity: b and t cells recognize antigenic determinants (epitopes), antigen has different parts to it that can be displayed, there are 1014 epitopes recognized by immune system. Tolerance of self: mature t-cells are (cid:858)educated(cid:859) i(cid:374) the thy(cid:373)us where they u(cid:374)dersta(cid:374)d that they must react to pathogens only or tumor/foreign cells, regulatory t-cells: destroy self-reactive t cells. Immunological memory: hallmark of immune system, the body remembers the pathogen it has encountered, rapid response, loss of immunological memory leads to repeat infections, you have to be exposed to the antigen to have the immunological memory. Secondary antibody response: primary: occurs the first time encounters the pathogen.

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BIOL 202 Lecture Notes - Lecture 9: Phagocytosis, Tetanospasmin, Plasma Cell

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