NUTR 132 Lecture 5: Fat Digestion

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Lipase: salivary lipase, gastric lipase, pancreatic lipase: pancreatic lipase is the most active lipase of all, fat breakdown is minimal until it gets to the small intestine. Digestion of fat in the small intestine: primary site of fat digestion, hormone: cholecystokinin (cck) Chyme in the small intestine stimulates the release of pancreatic lipase: bile acid released when chyme enters. Emulsifies digested fat (allows it to mix together: fat is broken down into monoglycerides and fatty acids in watery digestive juices. Digestion of phospholipids: enzymes are released from the pancreas and the cells of the small intestine, broken down into glycerol, fatty acids, and remaining parts. Digestion of cholesterol: enzymes are released from the pancreas, cholesterol is absorbed. Absorption: 95% of dietary fat is absorbed, diffused into the absorptive cells, short- and medium-chain (<12 c) fatty acids. Enter the portal system (circulatory system: long-chain fatty acids reform into triglycerides.

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